Pachydermoperiostosis:
imaging findings and differential diagnosis
Abstract
Pachydermoperiostosis, also known as primary hypertrophic osteoarthropathy, is a rare hereditary
disease characterized by soft tissue proliferation and periosteal new bone formation in long bones,
classically presenting with digital clubbing, symmetric periostosis, and joint effusions. Imaging studies
play a fundamental role in evaluating the extent of osteoarticular involvement. We report the case of
a patient with pachydermoperiostosis with knee joint involvement, highlighting magnetic resonance
imaging findings.
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References
Abdullah NRA, Jason WLC, Nasruddin AB. Pachydermoperiostosis: a rare mimic of acromegaly. Endocrinol Diabetes Metab Case Rep. 2017;2017:170029. Doi: 10.1530/EDM-17-0029.
Yap FY, Skalski MR, Patel DB, Schein AJ, White EA, Tomasian A, et al. Hypertrophic osteoarthropathy: clinical and imaging features. Radiographics. 2017;37(1):157–195. doi: 10.1148/rg.2017160052.
Adams B, Amin T, Leone V, Wood M, Kraft JK. Primary hypertrophic osteoarthropathy: ultrasound and MRI findings. Pediatr Radiol. 2016;46(5):727–730. doi: 10.1007/s00247-016-3544-8
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