O registro transcutâneo de CO2 contribui para a subclassificação das apneias do sono
Resumo
A hipercapnia resultante da apneia do sono é uma consequência fisiopatológica significativa que pode levar à disfunção cardíaca, circulatória, neurológica e renal. É um assunto de pesquisa recente, desde que a medição transcutânea de CO2 está disponível. Sua prevalência em pacientes com síndrome da apneia do sono e seus fatores preditivos não são totalmente conhecidos. Embora diferentes fenótipos de apneia do sono tenham sido descritos, o registro de PtCO2 não tem sido frequentemente usado para sua classificação. O objetivo deste estudo é apresentar o dados de 242 pacientes que consultaram por apneia do sono, que foram submetidos a polissonografia completa e pressão transcutânea de CO2. Aumento de CO2 durante o sono estava presente em 23.6% dos pacientes. O valor de PtCO2 ao acordar permitiu classificá-los em grupos com diferentes graus de gravidade e foi o mais importante preditor de aumento. Bicarbonato plasmático, tempo gasto em apneias e períodos de sono REM com dessaturação persistente de oxigênio foram eventos frequentemente associados. A inclusão da hipercapnia do sono entre as características para subclassificação da síndrome pode contribuir para um tratamento específico e personalizado.
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Copyright (c) 2025 Mariana Ksiazenicki, Ana Musetti, Florencia Artola, Fernanda Escuder, Lilian Chiappella, Gimena González, José Pedro Arcos, Gabriela Santa Marina, Lucía Morales, Rossana Frattini
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