Prevalencia de trombocitopenias en pacientes del Hospital de Clínicas en el periodo 2019 -2020

Abstract

Thrombocytopenia is defined as a platelet count below 100 x
103 platelets/ mm3 on the complete blood count. Epidemiological
data on thrombocytopenia are scarce and we lack local studies to
guide the clinician in its management. The objective of this work
was to describe thrombocytopenias in a sample of patients who
underwent blood counts at the Hospital de Clínicas in 2019-2020.
A prevalence study was carried out by collecting data from the
computerized registration of the hospital’s Clinical Laboratory. From
a sample of 11,128 patients, a complete blood count of each one
was randomly chosen, the sample distribution of platelet counts
by sex was studied, and the prevalence of thrombocytopenia
and pseudothrombocytopenia was determined. Prevalence of
thrombocytopenia was compared by age, sex and origin within
the institution and classified by severity and association with other
cytopenias. Mean platelet counts were lower in males (p < 0.0001).
An overall prevalence of 2.6% for thrombocytopenia and 0.1% for
pseudothrombocytopenia was determined. The prevalence of
thrombocytopenia was higher in males (OR= 1,7). The most prevalent
age groups were 31-50 years old and over 70 years old for males
and females, respectively. Mild thrombocytopenias represented
68% and the highest prevalence occurred in Hematology patients
and in hospitalized patients. This is the first study that describes
thrombocytopenias in a national health center and its findings could
contribute to the development of future research.