Physiopathological changes and complications of liver resections
Keywords:
liver surgery, hepatectomy morbidity, hepatectomy postoperative
Abstract
Modern surgical and anesthetic techniques have made it possible to increase the number of liver surgeries for various pathologies. This has reduced morbidity but still maintains high levels of morbidity. During hepatic surgery, hemodynamic changes related to liver mobilization, clamping and blood loss occur independently of the approach route. In the postoperative period, complications or pathophysiological changes derive from the lesions produced by ischemia and reperfusion phenomena; and those produced by hepatic regeneration. This capacity depends not only on the amount of remaining liver but also on the possible pre-existing hepatopathy.
Postoperative liver failure is the most feared complication and manifests with jaundice, ascites,
encephalopathy and paraclinical alterations such as hyperbilirubinemia and decreased prothrombin time.
Surgical complications depend on the procedure performed and are mainly divided into biliary and vascular.
The sequelae of hepatectomies depend on factors such as the patient's general condition, the presence of
liver disease, the surgical procedure and the quantity and quality of the remaining liver.
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References
1. Birkmeyer JD, Stukel TA, Siewers AE, Goodney PP, Wennberg DE, Lucas FL. Surgeon Volume and Operative Mortality in the United States. N Engl J Med. 2003 Nov 27;349(22):2117–27.
2. Finlayson EVA, Goodney PP, Birkmeyer JD, Davies RJ. Hospital volume and operative mortality in cancer surgery: A national study. Arch Surg. 2003 Jul 1;138(7):721–6.
3. McKay A, You I, Bigam D, Lafreniere R, Sutherland F, Ghali W, et al. Impact of surgeon training on outcomes after resective hepatic surgery. Ann Surg Oncol [Internet]. 2008 May [cited 2019 Dec 27];15(5):1348–55. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18306973
4. Pang YY. The Brisbane 2000 Terminology of Liver Anatomy and Resections. HPB 2000; 2:333-39. Vol. 16, Dig Surg. 1999.
5. Castaing D, Cotta FP, Salloum C. Conduite générale des hépatectomies par laparotomie. EMC - Tech Chir - Appar Dig. 2011 Jan;6(2):1–19.
6. Kamiyama T, Nakanishi K, Yokoo H, Kamachi H, Tahara M, Yamashita K, et al. Perioperative management of hepatic resection toward zero mortality and morbidity: analysis of 793 consecutive cases in a single institution. J Am Coll Surg [Internet]. 2010 Oct [cited 2019 Dec 27];211(4):443–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20822741
7. Kingham TP, Correa-Gallego C, I D’angelica M, Gönen M, Dematteo RP, Fong Y, et al. Hepatic Parenchymal Preservation Surgery: Decreasing Morbidity and Mortality Rates in 4,152 Resections for Malignancy.
8. Yokoo H, Miyata H, Konno H, Taketomi A, Kakisaka T, Hirahara N, et al. Models predicting the risks of six life-threatening morbidities and bile leakage in 14,970 hepatectomy patients registered in the National Clinical Database of Japan. Med (United States). 2016;95(49):e5466.
9. Alonso Casado A, Loinaz Segurola C, Moreno González E, Pérez Saborido B, Rico Selas P, González Pinto I, et al. Complicaciones de las resecciones hepáticas. Cir Esp. 2001;69(3):297–303.
10. Schreckenbach T, Liese J, Bechstein WO, Moench C. Posthepatectomy liver failure. Dig Surg. 2012 Mar;29(1):79–85.
11. Guglielmi A, Ruzzenente A, Conci S, Valdegamberi A, Iacono C. How much remnant is enough in liver resection? Dig Surg. 2012 Mar;29(1):6–17.
12. Etra JW, Squires MH, Fisher SB, Rutz DR, Martin BM, Kooby DA, et al. Early identification of patients at increased risk for hepatic insufficiency, complications and mortality after major hepatectomy. HPB (Oxford) [Internet]. 2014 Oct [cited 2019 Dec 27];16(10):875–83. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24836954
13. Lafaro K, Buettner S, Maqsood H, Wagner D, Bagante F, Spolverato G, et al. Defining Post Hepatectomy Liver Insufficiency: Where do We stand? J Gastrointest Surg [Internet]. 2015 Nov [cited 2019 Dec 27];19(11):2079–92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26063080
14. Rahbari NN, Garden OJ, Padbury R, Brooke-Smith M, Crawford M, Adam R, et al. Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS). Surgery. 2011 May;149(5):713–24.
15. Reissfelder C, Rahbari NN, Koch M, Kofler B, Sutedja N, Elbers H, et al. Postoperative course and clinical significance of biochemical blood tests following hepatic resection. Br J Surg [Internet]. 2011 Jun [cited 2019 Dec 28];98(6):836–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21456090
16. Balzan S, Belghiti J, Farges O, Ogata S, Sauvanet A, Delefosse D, et al. The “50-50 criteria” on postoperative day 5: An accurate predictor of liver failure and death after hepatectomy. In: Annals of Surgery. 2005. p. 824–9.
17. Mullen JT, Ribero D, Reddy SK, Donadon M, Zorzi D, Gautam S, et al. Hepatic Insufficiency and Mortality in 1,059 Noncirrhotic Patients Undergoing Major Hepatectomy. J Am Coll Surg. 2007 May;204(5):854–62.
18. Nanashima A, Abo T, Nonaka T, Fukuoka H, Hidaka S, Takeshita H, et al. Prognosis of patients with hepatocellular carcinoma after hepatic resection: Are elderly patients suitable for surgery? J Surg Oncol. 2011 Sep 1;104(3):284–91.
19. Kim JM, Cho BI, Kwon CHD, Joh J-W, Park JB, Lee JH, et al. Hepatectomy is a reasonable option for older patients with hepatocellular carcinoma. Am J Surg [Internet]. 2015 Feb [cited 2019 Dec 27];209(2):391–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25682096
20. Huo T-I, Lui W-Y, Huang Y-H, Chau G-Y, Wu J-C, Lee P-C, et al. Diabetes mellitus is a risk factor for hepatic decompensation in patients with hepatocellular carcinoma undergoing resection: a longitudinal study. Am J Gastroenterol [Internet]. 2003 Oct [cited 2019 Dec 27];98(10):2293–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/14572582
21. Little SA, Jarnagin WR, DeMatteo RP, Blumgart LH, Fong Y. Diabetes is associated with increased perioperative mortality but equivalent long-term outcome after hepatic resection for colorectal cancer. J Gastrointest Surg. 2002;6(1):88–94.
22. Hyder O, Pulitano C, Firoozmand A, Dodson R, Wolfgang CL, Choti MA, et al. A risk model to predict 90-day mortality among patients undergoing hepatic resection. J Am Coll Surg. 2013 Jun;216(6):1049–56.
23. Cucchetti A, Cescon M, Ercolani G, Di Gioia P, Peri E, Pinna AD. Safety of hepatic resection in overweight and obese patients with cirrhosis. Br J Surg. 2011 Aug;98(8):1147–54.
24. Kaibori M, Inoue T, Sakakura Y, Oda M, Nagahama T, Kwon AH, et al. Impairment of activation of hepatocyte growth factor precursor into its mature form in rats with liver cirrhosis. J Surg Res [Internet]. 2002 Jul [cited 2019 Dec 27];106(1):108–14. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12127815
25. Corpechot C, Barbu V, Wendum D, Chignard N, Housset C, Poupon R, et al. Hepatocyte growth factor and c-Met inhibition by hepatic cell hypoxia: a potential mechanism for liver regeneration failure in experimental cirrhosis. Am J Pathol [Internet]. 2002 Feb [cited 2019 Dec 27];160(2):613–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11839582
26. Bismuth H, Houssin D, Ornowski J, Meriggi F. Liver resections in cirrhotic patients: a Western experience. World J Surg [Internet]. 1986 Apr [cited 2019 Dec 27];10(2):311–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3010585
27. Poon RTP, Fan ST, Lo CM, Liu CL, Lam CM, Yuen WK, et al. Extended hepatic resection for hepatocellular carcinoma in patients with cirrhosis: Is it justified? Ann Surg. 2002 Nov 1;236(5):602–11.
28. Capussotti L, Muratore A, Amisano M, Polastri R, Bouzari H, Massucco P. Liver resection for hepatocellular carcinoma on cirrhosis: analysis of mortality, morbidity and survival--a European single center experience. Eur J Surg Oncol [Internet]. 2005 Nov [cited 2019 Dec 28];31(9):986–93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15936169
29. Eguchi H, Umeshita K, Sakon M, Nagano H, Ito Y, Kishimoto SI, et al. Presence of active hepatitis associated with liver cirrhosis is a risk factor for mortality caused by posthepatectomy liver failure. Dig Dis Sci. 2000;45(7):1383–8.
30. Selzner M, Clavien PA. Failure of regeneration of the steatotic rat liver: disruption at two different levels in the regeneration pathway. Hepatology [Internet]. 2000 Jan [cited 2019 Dec 28];31(1):35–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10613725
31. De Meijer VE, Kalish BT, Puder M, IJzermans JNM. Systematic review and meta-analysis of steatosis as a risk factor in major hepatic resection. Vol. 97, British Journal of Surgery. 2010. p. 1331–9.
32. Reddy SK, Marsh JW, Varley PR, Mock BK, Chopra KB, Geller DA, et al. Underlying steatohepatitis, but not simple hepatic steatosis, increases morbidity after liver resection: A case-control study. Hepatology. 2012 Dec;56(6):2221–30.
33. Robinson SM, Wilson CH, Burt AD, Manas DM, White SA. Chemotherapy-associated liver injury in patients with colorectal liver metastases: A systematic review and meta-analysis. Vol. 19, Annals of Surgical Oncology. 2012. p. 4287–99.
34. Zhao J, van Mierlo KMC, Gómez-Ramírez J, Kim H, Pilgrim CHC, Pessaux P, et al. Systematic review of the influence of chemotherapy-associated liver injury on outcome after partial hepatectomy for colorectal liver metastases. Vol. 104, British Journal of Surgery. John Wiley and Sons Ltd; 2017. p. 990–1002.
35. Karoui M, Penna C, Amin-Hashem M, Mitry E, Benoist S, Franc B, et al. Influence of preoperative chemotherapy on the risk of major hepatectomy for colorectal liver metastases. Ann Surg. 2006 Jan;243(1):1–7.
36. Nakano H, Oussoultzoglou E, Rosso E, Casnedi S, Chenard-Neu M-P, Dufour P, et al. Sinusoidal injury increases morbidity after major hepatectomy in patients with colorectal liver metastases receiving preoperative chemotherapy. Ann Surg [Internet]. 2008 Jan [cited 2019 Dec 28];247(1):118–24. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18156931
37. Pessaux P. [Chemotherapy’s hepatotoxicity: what is the impact on surgery?]. J Chir (Paris) [Internet]. 2010 Jan [cited 2019 Dec 28];147 Suppl 1:S7–11. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20172202
38. Poon RT, Fan ST, Lo CM, Liu CL, Lam CM, Yuen WK, et al. Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: Analysis of 1222 consecutive patients from a prospective database. In: Annals of Surgery. 2004. p. 698–710.
39. Imamura H, Seyama Y, Kokudo N, Maema A, Sugawara Y, Sano K, et al. One thousand fifty-six hepatectomies without mortality in 8 years. Arch Surg [Internet]. 2003 Nov [cited 2019 Dec 28];138(11):1198–206; discussion 1206. Available from: http://www.ncbi.nlm.nih.gov/pubmed/14609867
40. Smyrniotis V, Kostopanagiotou G, Theodoraki K, Tsantoulas D, Contis JC. The role of central venous pressure and type of vascular control in blood loss during major liver resections. Am J Surg. 2004 Mar;187(3):398–402.
41. Hughes MJ, Ventham NT, Harrison EM, Wigmore SJ. Central venous pressure and liver resection: A systematic review and meta-analysis. Vol. 17, HPB. Blackwell Publishing Ltd; 2015. p. 863–71.
42. Abdalla EK, Adam R, Bilchik AJ, Jaeck D, Vauthey JN, Mahvi D. Improving resectability of hepatic colorectal metastases: Expert consensus statement. In: Annals of Surgical Oncology. 2006. p. 1271–80.
43. Grande L, Roselló-Catafau J, Peralta C. El preacondicionamiento isquémico del hígado: De las bases moleculares a la aplicación clínica. Vol. 80, Cirugia Espanola. Ediciones Doyma, S.L.; 2006. p. 275–82.
44. Pittau G., Laurenzi A. CD. Séquelle des hépatectomies. EMC - Hépatologie [Internet]. 2017 [cited 2020 Jan 16];13(2):1–10. Available from: https://www.em-consulte.com/es/article/1147680/sequelles-des-hepatectomies
45. Orue-echebarria MI, Lozano P, Olmedilla L, Sabrido JLG, Asencio JM. “ Small-for-Flow ” Syndrome : Concept Evolution. 2020;(January):1386–91.
46. Allard MA, Adam R, Bucur PO, Termos S, Cunha AS, Bismuth H, et al. Posthepatectomy portal vein pressure predicts liver failure and mortality after major liver resection on noncirrhotic liver. Ann Surg. 2013;258(5):822–30.
47. Martel G, Cieslak KP, Huang R, Van Lienden KP, Wiggers JK, Belblidia A, et al. Comparison of techniques for volumetric analysis of the future liver remnant: Implications for major hepatic resections. In: HPB. Blackwell Publishing Ltd; 2015. p. 1051–7.
48. Vauthey J-N, Abdalla EK, Doherty DA, Gertsch P, Fenstermacher MJ, Loyer EM, et al. Body surface area and body weight predict total liver volume in Western adults. Liver Transpl [Internet]. 2002 Mar [cited 2019 Dec 28];8(3):233–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11910568
49. Ribero D, Amisano M, Bertuzzo F, Langella S, Lo Tesoriere R, Ferrero A, et al. Measured versus estimated total liver volume to preoperatively assess the adequacy of the future liver remnant: Which method should we use? Ann Surg. 2013 Nov;258(5):801–7.
50. Wibmer A, Prusa AM, Nolz R, Gruenberger T, Schindl M, Ba-Ssalamah A. Liver failure after major liver resection: risk assessment by using preoperative Gadoxetic acid-enhanced 3-T MR imaging. Radiology [Internet]. 2013 Dec [cited 2019 Dec 28];269(3):777–86. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23942606
51. Kinoshita H, Sakai K, Hirohashi K, Igawa S, Yamasaki O, Kubo S. Preoperative portal vein embolization for hepatocellular carcinoma. World J Surg [Internet]. 1986 Oct [cited 2019 Dec 28];10(5):803–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3022488
52. Golse N, Bucur PO, Adam R, Castaing D, Sa Cunha A, Vibert E. New paradigms in post-hepatectomy liver failure. J Gastrointest Surg [Internet]. 2013 Mar [cited 2019 Dec 28];17(3):593–605. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23161285
53. Abulkhir A, Limongelli P, Healey AJ, Damrah O, Tait P, Jackson J, et al. Preoperative portal vein embolization for major liver resection: A meta-analysis. Ann Surg. 2008 Jan;247(1):49–57.
54. Adam R, Laurent A, Azoulay D, Castaing D, Bismuth H, Buchler M, et al. Two-stage hepatectomy: A planned strategy to treat irresectable liver tumors. Ann Surg. 2000;232(6):777–85.
55. Tsai S, Marques HP, De Jong MC, Mira P, Ribeiro V, Choti MA, et al. Two-stage strategy for patients with extensive bilateral colorectal liver metastases. HPB. 2010;12(4):262–9.
56. Pandanaboyana S, Bell R, Hidalgo E, Toogood G, Prasad KR, Bartlett A, et al. A systematic review and meta-analysis of portal vein ligation versus portal vein embolization for elective liver resection. Surgery [Internet]. 2015 Apr [cited 2019 Dec 28];157(4):690–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25704417
57. Schnitzbauer AA, Lang SA, Goessmann H, Nadalin S, Baumgart J, Farkas SA, et al. Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings. Ann Surg. 2012 Mar;255(3):405–14.
58. Zhang GQ, Zhang ZW, Lau WY, Chen XP. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): A new strategy to increase resectability in liver surgery. Int J Surg. 2014;12(5):437–41.
59. Jin S, Fu Q, Wuyun G, Wuyun T. Management of post-hepatectomy complications. Vol. 19, World Journal of Gastroenterology. 2013. p. 7983–91.
60. Rahimi RS, Singal AG, Cuthbert JA, Rockey DC. Lactulose vs polyethylene glycol 3350--electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial. JAMA Intern Med [Internet]. 2014 Nov [cited 2019 Dec 28];174(11):1727–33. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25243839
61. Leithead JA, Ferguson JW, Bates CM, Davidson JS, Lee A, Bathgate AJ, et al. The systemic inflammatory response syndrome is predictive of renal dysfunction in patients with non-paracetamol-induced acute liver failure. Gut [Internet]. 2009 Mar [cited 2019 Dec 28];58(3):443–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19001057
62. Yadav K, Shrikhande S, Goel M. Post hepatectomy liver failure: concept of management. J Gastrointest Cancer [Internet]. 2014 Dec [cited 2019 Dec 28];45(4):405–13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25104504
63. Steiner C, Mitzner S. Experiences with MARS liver support therapy in liver failure: analysis of 176 patients of the International MARS Registry. Liver [Internet]. 2002 [cited 2019 Dec 28];22 Suppl 2:20–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12220298
64. van de Kerkhove MP, de Jong KP, Rijken AM, de Pont ACJM, van Gulik TM. MARS treatment in posthepatectomy liver failure. Liver Int. 2003;23(SUPPL. 3):44–51.
65. Chan SC, Sharr WW, Chan ACY, Chok KSH, Lo CM. Rescue Living-donor Liver Transplantation for Liver Failure Following Hepatectomy for Hepatocellular Carcinoma. Liver cancer [Internet]. 2013 Aug [cited 2019 Dec 28];2(3–4):332–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24400220
66. Cockbain AJ, Masudi T, Lodge JPA, Toogood GJ, Prasad KR. Predictors of blood transfusion requirement in elective liver resection. HPB. 2010;12(1):50–5.
67. Bennett S, Baker L, Shorr R, Martel G, Fergusson D. The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review protocol. Syst Rev [Internet]. 2016 Feb 29 [cited 2019 Dec 28];5:38. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26926289
68. Kooby DA, Stockman J, Ben-Porat L, Gonen M, Jarnagin WR, Dematteo RP, et al. Influence of transfusions on perioperative and long-term outcome in patients following hepatic resection for colorectal metastases. Ann Surg [Internet]. 2003 Jun [cited 2019 Dec 28];237(6):860–9; discussion 869-70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12796583
69. Hallet J, Tsang M, Cheng ESW, Habashi R, Kulyk I, Hanna SS, et al. The Impact of Perioperative Red Blood Cell Transfusions on Long-Term Outcomes after Hepatectomy for Colorectal Liver Metastases. Ann Surg Oncol [Internet]. 2015 Nov [cited 2019 Dec 28];22(12):4038–45. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25752895
70. Schiergens TS, Rentsch M, Kasparek MS, Frenes K, Jauch K-W, Thasler WE. Impact of perioperative allogeneic red blood cell transfusion on recurrence and overall survival after resection of colorectal liver metastases. Dis Colon Rectum [Internet]. 2015 Jan [cited 2019 Dec 28];58(1):74–82. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25489697
71. Amato A, Pescatori M. Perioperative blood transfusions for the recurrence of colorectal cancer. Cochrane database Syst Rev [Internet]. 2006 Jan 25 [cited 2019 Dec 28];(1):CD005033. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16437512
72. Spolverato G, Ejaz A, Kim Y, Hall BL, Bilimoria K, Cohen M, et al. Patterns of care among patients undergoing hepatic resection: a query of the National Surgical Quality Improvement Program-targeted hepatectomy database. J Surg Res [Internet]. 2015 Jun 15 [cited 2019 Dec 28];196(2):221–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25881789
73. Rahbari NN, Garden OJ, Padbury R, Maddern G, Koch M, Hugh TJ, et al. Post-hepatectomy haemorrhage: a definition and grading by the International Study Group of Liver Surgery (ISGLS). HPB (Oxford) [Internet]. 2011 Aug [cited 2019 Dec 28];13(8):528–35. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21762295
74. Reissfelder C, Rahbari NN, Koch M, Kofler B, Sutedja N, Elbers H, et al. Postoperative course and clinical significance of biochemical blood tests following hepatic resection. Br J Surg [Internet]. 2011 Jun [cited 2019 Dec 27];98(6):836–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21456090
75. Guillaud A, Pery C, Campillo B, Lourdais A, Sulpice L, Laurent S, et al. Incidence and predictive factors of clinically relevant bile leakage in the modern era of liver resections. HPB (Oxford) [Internet]. 2013 Mar [cited 2019 Dec 28];15(3):224–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23374363
76. Wang HQ, Yang J, Yang JY, Yan LN. Bile leakage test in liver resection: A systematic review and meta-analysis. World J Gastroenterol. 2013;19(45):8420–6.
77. Calatayud D, Sánchez Cabús S, Sampson J, Resendiz A, Molina V, Fondevila C, et al. Resección hepática mayor: una cirugía segura y eficaz. Cir Esp. 2017 Oct 1;95(8):437–46.
78. Koch M, Garden OJ, Padbury R, Rahbari NN, Adam R, Capussotti L, et al. Bile leakage after hepatobiliary and pancreatic surgery: a definition and grading of severity by the International Study Group of Liver Surgery. Surgery [Internet]. 2011 May [cited 2019 Dec 28];149(5):680–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21316725
79. Kajiwara T, Midorikawa Y, Yamazaki S, Higaki T, Nakayama H, Moriguchi M, et al. Clinical score to predict the risk of bile leakage after liver resection. BMC Surg [Internet]. 2016 May 6 [cited 2019 Dec 28];16(1):30. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27154038
80. Yoshiya S, Shirabe K, Nakagawara H, Soejima Y, Yoshizumi T, Ikegami T, et al. Portal vein thrombosis after hepatectomy. World J Surg. 2014;38(6):1491–7.
81. Han JH, Kim DS, Yu YD, Jung SW, Yoon YI, Jo HS. Analysis of risk factors for portal vein thrombosis after liver resection. Ann Surg Treat Res. 2019;96(5):230–6.
82. Russell MC. Complications following hepatectomy. Surg Oncol Clin N Am [Internet]. 2015;24(1):73–96. Available from: http://dx.doi.org/10.1016/j.soc.2014.09.008
83. Di Domenico S, Rossini A, Petrocelli F, Valente U, Ferro C. Recurrent acute Budd-Chiari syndrome after right hepatectomy: US color-Doppler vascular pattern and left hepatic vein stenting for treatment. Abdom Imaging. 2013;38(2):320–3.
84. Wang JK, Truty MJ, Donohue JH. Remnant torsion causing budd-chiari syndrome after right hepatectomy. J Gastrointest Surg. 2010;14(5):910–2.
85- Gnannt, R.; Fischer, M.A.; Baechler, T.; Clavien, P.-A.; Karlo, C.; Seifert, B.; Lesurtel, M.; Alkadhi, H. Distinguishing Infected From Noninfected Abdominal Fluid Collections After Surgery. Investig. Radiol. 2015, 50, 17–23.
86- Camacho, J.C.; Coursey-Moreno, C.; Telleria, J.C.; Aguirre, D.A.; Torres, W.E.; Mittal, P.K. Nonvascular Post–Liver Transplantation Complications: From US Screening to Cross-sectional and Interventional Imaging.Radiographics 2015, 35, 87–104.
87- Brook, I. Microbiology and Management of Abdominal Infections. Dig. Dis. Sci. 2008, 53, 2585–2591.
88- Benzoni, E.; Cojutti, A.; Lorenzin, D.; Adani, G.L.; Baccarani, U.; Favero, A.; Zompicchiati, A.; Bresadola, F.; Uzzau, A. Liver resective surgery: A multivariate analysis of postoperative outcome and complication. Langenbeck’s Arch. Surg. 2006, 392, 45–54.
89 - Arikawa T, Kurokawa T, Ohwa Y, et al. Risk factors for surgical site infection after hepatectomy for hepatocellular carcinoma. Hepatogastroenterology. 58(105):143-146. http://www.ncbi.nlm.nih.gov/pubmed/21510302. Accessed October 8, 2018
90- Winter, K.S.; Greif, V.;Crispin, A.; Burgard, C.; Forbrig, R.; Liebig, T.; Trumm, C.G.; Stahl, R. CT-Guided Drainage of Fluid Collections Following Liver Resection: Technical and Clinical Outcome of 143 Patients during 14-Year Period. Diagnostics 2021, 11, 826.
91- Mulé S, Colosio A, Cazejust J, Kianmanesh R, Soyer P, Hoeffel C. Imaging of the postoperative liver: review of normal appearances and common complications. Abdom Imaging. 2015;40(7):2761-2776. doi:10.1007/s00261-015-0459-z
92- Brustia, R.; Fleres, F.; Tamby, E.; Rhaiem, R.; Piardi, T.; Kianmanesh, R.; Sommacale, D. Postoperative collections after liver surgery: Risk factors and impact on long-term outcomes. J. Visc. Surg. 2020, 157, 199–209.
93-Rathmann, N.; Haeusler, U.; Diezler, P.; Weiss, C.; Kostrzewa, M.; Sadick, M.; Schoenberg, S.O.; Diehl, S.J. Evaluation of Radiation Exposure of Medical Staff During CT-Guided Interventions. J. Am. Coll. Radiol. 2015, 12, 82–89.
94- Vansonnenberg, M.E.;Wittich, M.G.R.; Goodacre, M.B.W.; Casola, M.G.; D’Agostino, M.H.B. Percutaneous Abscess Drainage: Update. World J. Surg. 2001, 25, 362–369.
95- Dorcaratto D, Mazzinari G, Fernandez M, et al. Impact of Postoperative Complications on Survival and Recurrence After Resection of Colorectal Liver Metastases. Ann Surg. February 2019:1. doi:10.1097/SLA.0000000000003254
2. Finlayson EVA, Goodney PP, Birkmeyer JD, Davies RJ. Hospital volume and operative mortality in cancer surgery: A national study. Arch Surg. 2003 Jul 1;138(7):721–6.
3. McKay A, You I, Bigam D, Lafreniere R, Sutherland F, Ghali W, et al. Impact of surgeon training on outcomes after resective hepatic surgery. Ann Surg Oncol [Internet]. 2008 May [cited 2019 Dec 27];15(5):1348–55. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18306973
4. Pang YY. The Brisbane 2000 Terminology of Liver Anatomy and Resections. HPB 2000; 2:333-39. Vol. 16, Dig Surg. 1999.
5. Castaing D, Cotta FP, Salloum C. Conduite générale des hépatectomies par laparotomie. EMC - Tech Chir - Appar Dig. 2011 Jan;6(2):1–19.
6. Kamiyama T, Nakanishi K, Yokoo H, Kamachi H, Tahara M, Yamashita K, et al. Perioperative management of hepatic resection toward zero mortality and morbidity: analysis of 793 consecutive cases in a single institution. J Am Coll Surg [Internet]. 2010 Oct [cited 2019 Dec 27];211(4):443–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20822741
7. Kingham TP, Correa-Gallego C, I D’angelica M, Gönen M, Dematteo RP, Fong Y, et al. Hepatic Parenchymal Preservation Surgery: Decreasing Morbidity and Mortality Rates in 4,152 Resections for Malignancy.
8. Yokoo H, Miyata H, Konno H, Taketomi A, Kakisaka T, Hirahara N, et al. Models predicting the risks of six life-threatening morbidities and bile leakage in 14,970 hepatectomy patients registered in the National Clinical Database of Japan. Med (United States). 2016;95(49):e5466.
9. Alonso Casado A, Loinaz Segurola C, Moreno González E, Pérez Saborido B, Rico Selas P, González Pinto I, et al. Complicaciones de las resecciones hepáticas. Cir Esp. 2001;69(3):297–303.
10. Schreckenbach T, Liese J, Bechstein WO, Moench C. Posthepatectomy liver failure. Dig Surg. 2012 Mar;29(1):79–85.
11. Guglielmi A, Ruzzenente A, Conci S, Valdegamberi A, Iacono C. How much remnant is enough in liver resection? Dig Surg. 2012 Mar;29(1):6–17.
12. Etra JW, Squires MH, Fisher SB, Rutz DR, Martin BM, Kooby DA, et al. Early identification of patients at increased risk for hepatic insufficiency, complications and mortality after major hepatectomy. HPB (Oxford) [Internet]. 2014 Oct [cited 2019 Dec 27];16(10):875–83. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24836954
13. Lafaro K, Buettner S, Maqsood H, Wagner D, Bagante F, Spolverato G, et al. Defining Post Hepatectomy Liver Insufficiency: Where do We stand? J Gastrointest Surg [Internet]. 2015 Nov [cited 2019 Dec 27];19(11):2079–92. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26063080
14. Rahbari NN, Garden OJ, Padbury R, Brooke-Smith M, Crawford M, Adam R, et al. Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS). Surgery. 2011 May;149(5):713–24.
15. Reissfelder C, Rahbari NN, Koch M, Kofler B, Sutedja N, Elbers H, et al. Postoperative course and clinical significance of biochemical blood tests following hepatic resection. Br J Surg [Internet]. 2011 Jun [cited 2019 Dec 28];98(6):836–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21456090
16. Balzan S, Belghiti J, Farges O, Ogata S, Sauvanet A, Delefosse D, et al. The “50-50 criteria” on postoperative day 5: An accurate predictor of liver failure and death after hepatectomy. In: Annals of Surgery. 2005. p. 824–9.
17. Mullen JT, Ribero D, Reddy SK, Donadon M, Zorzi D, Gautam S, et al. Hepatic Insufficiency and Mortality in 1,059 Noncirrhotic Patients Undergoing Major Hepatectomy. J Am Coll Surg. 2007 May;204(5):854–62.
18. Nanashima A, Abo T, Nonaka T, Fukuoka H, Hidaka S, Takeshita H, et al. Prognosis of patients with hepatocellular carcinoma after hepatic resection: Are elderly patients suitable for surgery? J Surg Oncol. 2011 Sep 1;104(3):284–91.
19. Kim JM, Cho BI, Kwon CHD, Joh J-W, Park JB, Lee JH, et al. Hepatectomy is a reasonable option for older patients with hepatocellular carcinoma. Am J Surg [Internet]. 2015 Feb [cited 2019 Dec 27];209(2):391–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25682096
20. Huo T-I, Lui W-Y, Huang Y-H, Chau G-Y, Wu J-C, Lee P-C, et al. Diabetes mellitus is a risk factor for hepatic decompensation in patients with hepatocellular carcinoma undergoing resection: a longitudinal study. Am J Gastroenterol [Internet]. 2003 Oct [cited 2019 Dec 27];98(10):2293–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/14572582
21. Little SA, Jarnagin WR, DeMatteo RP, Blumgart LH, Fong Y. Diabetes is associated with increased perioperative mortality but equivalent long-term outcome after hepatic resection for colorectal cancer. J Gastrointest Surg. 2002;6(1):88–94.
22. Hyder O, Pulitano C, Firoozmand A, Dodson R, Wolfgang CL, Choti MA, et al. A risk model to predict 90-day mortality among patients undergoing hepatic resection. J Am Coll Surg. 2013 Jun;216(6):1049–56.
23. Cucchetti A, Cescon M, Ercolani G, Di Gioia P, Peri E, Pinna AD. Safety of hepatic resection in overweight and obese patients with cirrhosis. Br J Surg. 2011 Aug;98(8):1147–54.
24. Kaibori M, Inoue T, Sakakura Y, Oda M, Nagahama T, Kwon AH, et al. Impairment of activation of hepatocyte growth factor precursor into its mature form in rats with liver cirrhosis. J Surg Res [Internet]. 2002 Jul [cited 2019 Dec 27];106(1):108–14. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12127815
25. Corpechot C, Barbu V, Wendum D, Chignard N, Housset C, Poupon R, et al. Hepatocyte growth factor and c-Met inhibition by hepatic cell hypoxia: a potential mechanism for liver regeneration failure in experimental cirrhosis. Am J Pathol [Internet]. 2002 Feb [cited 2019 Dec 27];160(2):613–20. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11839582
26. Bismuth H, Houssin D, Ornowski J, Meriggi F. Liver resections in cirrhotic patients: a Western experience. World J Surg [Internet]. 1986 Apr [cited 2019 Dec 27];10(2):311–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3010585
27. Poon RTP, Fan ST, Lo CM, Liu CL, Lam CM, Yuen WK, et al. Extended hepatic resection for hepatocellular carcinoma in patients with cirrhosis: Is it justified? Ann Surg. 2002 Nov 1;236(5):602–11.
28. Capussotti L, Muratore A, Amisano M, Polastri R, Bouzari H, Massucco P. Liver resection for hepatocellular carcinoma on cirrhosis: analysis of mortality, morbidity and survival--a European single center experience. Eur J Surg Oncol [Internet]. 2005 Nov [cited 2019 Dec 28];31(9):986–93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15936169
29. Eguchi H, Umeshita K, Sakon M, Nagano H, Ito Y, Kishimoto SI, et al. Presence of active hepatitis associated with liver cirrhosis is a risk factor for mortality caused by posthepatectomy liver failure. Dig Dis Sci. 2000;45(7):1383–8.
30. Selzner M, Clavien PA. Failure of regeneration of the steatotic rat liver: disruption at two different levels in the regeneration pathway. Hepatology [Internet]. 2000 Jan [cited 2019 Dec 28];31(1):35–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/10613725
31. De Meijer VE, Kalish BT, Puder M, IJzermans JNM. Systematic review and meta-analysis of steatosis as a risk factor in major hepatic resection. Vol. 97, British Journal of Surgery. 2010. p. 1331–9.
32. Reddy SK, Marsh JW, Varley PR, Mock BK, Chopra KB, Geller DA, et al. Underlying steatohepatitis, but not simple hepatic steatosis, increases morbidity after liver resection: A case-control study. Hepatology. 2012 Dec;56(6):2221–30.
33. Robinson SM, Wilson CH, Burt AD, Manas DM, White SA. Chemotherapy-associated liver injury in patients with colorectal liver metastases: A systematic review and meta-analysis. Vol. 19, Annals of Surgical Oncology. 2012. p. 4287–99.
34. Zhao J, van Mierlo KMC, Gómez-Ramírez J, Kim H, Pilgrim CHC, Pessaux P, et al. Systematic review of the influence of chemotherapy-associated liver injury on outcome after partial hepatectomy for colorectal liver metastases. Vol. 104, British Journal of Surgery. John Wiley and Sons Ltd; 2017. p. 990–1002.
35. Karoui M, Penna C, Amin-Hashem M, Mitry E, Benoist S, Franc B, et al. Influence of preoperative chemotherapy on the risk of major hepatectomy for colorectal liver metastases. Ann Surg. 2006 Jan;243(1):1–7.
36. Nakano H, Oussoultzoglou E, Rosso E, Casnedi S, Chenard-Neu M-P, Dufour P, et al. Sinusoidal injury increases morbidity after major hepatectomy in patients with colorectal liver metastases receiving preoperative chemotherapy. Ann Surg [Internet]. 2008 Jan [cited 2019 Dec 28];247(1):118–24. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18156931
37. Pessaux P. [Chemotherapy’s hepatotoxicity: what is the impact on surgery?]. J Chir (Paris) [Internet]. 2010 Jan [cited 2019 Dec 28];147 Suppl 1:S7–11. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20172202
38. Poon RT, Fan ST, Lo CM, Liu CL, Lam CM, Yuen WK, et al. Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: Analysis of 1222 consecutive patients from a prospective database. In: Annals of Surgery. 2004. p. 698–710.
39. Imamura H, Seyama Y, Kokudo N, Maema A, Sugawara Y, Sano K, et al. One thousand fifty-six hepatectomies without mortality in 8 years. Arch Surg [Internet]. 2003 Nov [cited 2019 Dec 28];138(11):1198–206; discussion 1206. Available from: http://www.ncbi.nlm.nih.gov/pubmed/14609867
40. Smyrniotis V, Kostopanagiotou G, Theodoraki K, Tsantoulas D, Contis JC. The role of central venous pressure and type of vascular control in blood loss during major liver resections. Am J Surg. 2004 Mar;187(3):398–402.
41. Hughes MJ, Ventham NT, Harrison EM, Wigmore SJ. Central venous pressure and liver resection: A systematic review and meta-analysis. Vol. 17, HPB. Blackwell Publishing Ltd; 2015. p. 863–71.
42. Abdalla EK, Adam R, Bilchik AJ, Jaeck D, Vauthey JN, Mahvi D. Improving resectability of hepatic colorectal metastases: Expert consensus statement. In: Annals of Surgical Oncology. 2006. p. 1271–80.
43. Grande L, Roselló-Catafau J, Peralta C. El preacondicionamiento isquémico del hígado: De las bases moleculares a la aplicación clínica. Vol. 80, Cirugia Espanola. Ediciones Doyma, S.L.; 2006. p. 275–82.
44. Pittau G., Laurenzi A. CD. Séquelle des hépatectomies. EMC - Hépatologie [Internet]. 2017 [cited 2020 Jan 16];13(2):1–10. Available from: https://www.em-consulte.com/es/article/1147680/sequelles-des-hepatectomies
45. Orue-echebarria MI, Lozano P, Olmedilla L, Sabrido JLG, Asencio JM. “ Small-for-Flow ” Syndrome : Concept Evolution. 2020;(January):1386–91.
46. Allard MA, Adam R, Bucur PO, Termos S, Cunha AS, Bismuth H, et al. Posthepatectomy portal vein pressure predicts liver failure and mortality after major liver resection on noncirrhotic liver. Ann Surg. 2013;258(5):822–30.
47. Martel G, Cieslak KP, Huang R, Van Lienden KP, Wiggers JK, Belblidia A, et al. Comparison of techniques for volumetric analysis of the future liver remnant: Implications for major hepatic resections. In: HPB. Blackwell Publishing Ltd; 2015. p. 1051–7.
48. Vauthey J-N, Abdalla EK, Doherty DA, Gertsch P, Fenstermacher MJ, Loyer EM, et al. Body surface area and body weight predict total liver volume in Western adults. Liver Transpl [Internet]. 2002 Mar [cited 2019 Dec 28];8(3):233–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/11910568
49. Ribero D, Amisano M, Bertuzzo F, Langella S, Lo Tesoriere R, Ferrero A, et al. Measured versus estimated total liver volume to preoperatively assess the adequacy of the future liver remnant: Which method should we use? Ann Surg. 2013 Nov;258(5):801–7.
50. Wibmer A, Prusa AM, Nolz R, Gruenberger T, Schindl M, Ba-Ssalamah A. Liver failure after major liver resection: risk assessment by using preoperative Gadoxetic acid-enhanced 3-T MR imaging. Radiology [Internet]. 2013 Dec [cited 2019 Dec 28];269(3):777–86. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23942606
51. Kinoshita H, Sakai K, Hirohashi K, Igawa S, Yamasaki O, Kubo S. Preoperative portal vein embolization for hepatocellular carcinoma. World J Surg [Internet]. 1986 Oct [cited 2019 Dec 28];10(5):803–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3022488
52. Golse N, Bucur PO, Adam R, Castaing D, Sa Cunha A, Vibert E. New paradigms in post-hepatectomy liver failure. J Gastrointest Surg [Internet]. 2013 Mar [cited 2019 Dec 28];17(3):593–605. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23161285
53. Abulkhir A, Limongelli P, Healey AJ, Damrah O, Tait P, Jackson J, et al. Preoperative portal vein embolization for major liver resection: A meta-analysis. Ann Surg. 2008 Jan;247(1):49–57.
54. Adam R, Laurent A, Azoulay D, Castaing D, Bismuth H, Buchler M, et al. Two-stage hepatectomy: A planned strategy to treat irresectable liver tumors. Ann Surg. 2000;232(6):777–85.
55. Tsai S, Marques HP, De Jong MC, Mira P, Ribeiro V, Choti MA, et al. Two-stage strategy for patients with extensive bilateral colorectal liver metastases. HPB. 2010;12(4):262–9.
56. Pandanaboyana S, Bell R, Hidalgo E, Toogood G, Prasad KR, Bartlett A, et al. A systematic review and meta-analysis of portal vein ligation versus portal vein embolization for elective liver resection. Surgery [Internet]. 2015 Apr [cited 2019 Dec 28];157(4):690–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25704417
57. Schnitzbauer AA, Lang SA, Goessmann H, Nadalin S, Baumgart J, Farkas SA, et al. Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings. Ann Surg. 2012 Mar;255(3):405–14.
58. Zhang GQ, Zhang ZW, Lau WY, Chen XP. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): A new strategy to increase resectability in liver surgery. Int J Surg. 2014;12(5):437–41.
59. Jin S, Fu Q, Wuyun G, Wuyun T. Management of post-hepatectomy complications. Vol. 19, World Journal of Gastroenterology. 2013. p. 7983–91.
60. Rahimi RS, Singal AG, Cuthbert JA, Rockey DC. Lactulose vs polyethylene glycol 3350--electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial. JAMA Intern Med [Internet]. 2014 Nov [cited 2019 Dec 28];174(11):1727–33. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25243839
61. Leithead JA, Ferguson JW, Bates CM, Davidson JS, Lee A, Bathgate AJ, et al. The systemic inflammatory response syndrome is predictive of renal dysfunction in patients with non-paracetamol-induced acute liver failure. Gut [Internet]. 2009 Mar [cited 2019 Dec 28];58(3):443–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19001057
62. Yadav K, Shrikhande S, Goel M. Post hepatectomy liver failure: concept of management. J Gastrointest Cancer [Internet]. 2014 Dec [cited 2019 Dec 28];45(4):405–13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25104504
63. Steiner C, Mitzner S. Experiences with MARS liver support therapy in liver failure: analysis of 176 patients of the International MARS Registry. Liver [Internet]. 2002 [cited 2019 Dec 28];22 Suppl 2:20–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12220298
64. van de Kerkhove MP, de Jong KP, Rijken AM, de Pont ACJM, van Gulik TM. MARS treatment in posthepatectomy liver failure. Liver Int. 2003;23(SUPPL. 3):44–51.
65. Chan SC, Sharr WW, Chan ACY, Chok KSH, Lo CM. Rescue Living-donor Liver Transplantation for Liver Failure Following Hepatectomy for Hepatocellular Carcinoma. Liver cancer [Internet]. 2013 Aug [cited 2019 Dec 28];2(3–4):332–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24400220
66. Cockbain AJ, Masudi T, Lodge JPA, Toogood GJ, Prasad KR. Predictors of blood transfusion requirement in elective liver resection. HPB. 2010;12(1):50–5.
67. Bennett S, Baker L, Shorr R, Martel G, Fergusson D. The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review protocol. Syst Rev [Internet]. 2016 Feb 29 [cited 2019 Dec 28];5:38. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26926289
68. Kooby DA, Stockman J, Ben-Porat L, Gonen M, Jarnagin WR, Dematteo RP, et al. Influence of transfusions on perioperative and long-term outcome in patients following hepatic resection for colorectal metastases. Ann Surg [Internet]. 2003 Jun [cited 2019 Dec 28];237(6):860–9; discussion 869-70. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12796583
69. Hallet J, Tsang M, Cheng ESW, Habashi R, Kulyk I, Hanna SS, et al. The Impact of Perioperative Red Blood Cell Transfusions on Long-Term Outcomes after Hepatectomy for Colorectal Liver Metastases. Ann Surg Oncol [Internet]. 2015 Nov [cited 2019 Dec 28];22(12):4038–45. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25752895
70. Schiergens TS, Rentsch M, Kasparek MS, Frenes K, Jauch K-W, Thasler WE. Impact of perioperative allogeneic red blood cell transfusion on recurrence and overall survival after resection of colorectal liver metastases. Dis Colon Rectum [Internet]. 2015 Jan [cited 2019 Dec 28];58(1):74–82. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25489697
71. Amato A, Pescatori M. Perioperative blood transfusions for the recurrence of colorectal cancer. Cochrane database Syst Rev [Internet]. 2006 Jan 25 [cited 2019 Dec 28];(1):CD005033. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16437512
72. Spolverato G, Ejaz A, Kim Y, Hall BL, Bilimoria K, Cohen M, et al. Patterns of care among patients undergoing hepatic resection: a query of the National Surgical Quality Improvement Program-targeted hepatectomy database. J Surg Res [Internet]. 2015 Jun 15 [cited 2019 Dec 28];196(2):221–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25881789
73. Rahbari NN, Garden OJ, Padbury R, Maddern G, Koch M, Hugh TJ, et al. Post-hepatectomy haemorrhage: a definition and grading by the International Study Group of Liver Surgery (ISGLS). HPB (Oxford) [Internet]. 2011 Aug [cited 2019 Dec 28];13(8):528–35. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21762295
74. Reissfelder C, Rahbari NN, Koch M, Kofler B, Sutedja N, Elbers H, et al. Postoperative course and clinical significance of biochemical blood tests following hepatic resection. Br J Surg [Internet]. 2011 Jun [cited 2019 Dec 27];98(6):836–44. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21456090
75. Guillaud A, Pery C, Campillo B, Lourdais A, Sulpice L, Laurent S, et al. Incidence and predictive factors of clinically relevant bile leakage in the modern era of liver resections. HPB (Oxford) [Internet]. 2013 Mar [cited 2019 Dec 28];15(3):224–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23374363
76. Wang HQ, Yang J, Yang JY, Yan LN. Bile leakage test in liver resection: A systematic review and meta-analysis. World J Gastroenterol. 2013;19(45):8420–6.
77. Calatayud D, Sánchez Cabús S, Sampson J, Resendiz A, Molina V, Fondevila C, et al. Resección hepática mayor: una cirugía segura y eficaz. Cir Esp. 2017 Oct 1;95(8):437–46.
78. Koch M, Garden OJ, Padbury R, Rahbari NN, Adam R, Capussotti L, et al. Bile leakage after hepatobiliary and pancreatic surgery: a definition and grading of severity by the International Study Group of Liver Surgery. Surgery [Internet]. 2011 May [cited 2019 Dec 28];149(5):680–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21316725
79. Kajiwara T, Midorikawa Y, Yamazaki S, Higaki T, Nakayama H, Moriguchi M, et al. Clinical score to predict the risk of bile leakage after liver resection. BMC Surg [Internet]. 2016 May 6 [cited 2019 Dec 28];16(1):30. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27154038
80. Yoshiya S, Shirabe K, Nakagawara H, Soejima Y, Yoshizumi T, Ikegami T, et al. Portal vein thrombosis after hepatectomy. World J Surg. 2014;38(6):1491–7.
81. Han JH, Kim DS, Yu YD, Jung SW, Yoon YI, Jo HS. Analysis of risk factors for portal vein thrombosis after liver resection. Ann Surg Treat Res. 2019;96(5):230–6.
82. Russell MC. Complications following hepatectomy. Surg Oncol Clin N Am [Internet]. 2015;24(1):73–96. Available from: http://dx.doi.org/10.1016/j.soc.2014.09.008
83. Di Domenico S, Rossini A, Petrocelli F, Valente U, Ferro C. Recurrent acute Budd-Chiari syndrome after right hepatectomy: US color-Doppler vascular pattern and left hepatic vein stenting for treatment. Abdom Imaging. 2013;38(2):320–3.
84. Wang JK, Truty MJ, Donohue JH. Remnant torsion causing budd-chiari syndrome after right hepatectomy. J Gastrointest Surg. 2010;14(5):910–2.
85- Gnannt, R.; Fischer, M.A.; Baechler, T.; Clavien, P.-A.; Karlo, C.; Seifert, B.; Lesurtel, M.; Alkadhi, H. Distinguishing Infected From Noninfected Abdominal Fluid Collections After Surgery. Investig. Radiol. 2015, 50, 17–23.
86- Camacho, J.C.; Coursey-Moreno, C.; Telleria, J.C.; Aguirre, D.A.; Torres, W.E.; Mittal, P.K. Nonvascular Post–Liver Transplantation Complications: From US Screening to Cross-sectional and Interventional Imaging.Radiographics 2015, 35, 87–104.
87- Brook, I. Microbiology and Management of Abdominal Infections. Dig. Dis. Sci. 2008, 53, 2585–2591.
88- Benzoni, E.; Cojutti, A.; Lorenzin, D.; Adani, G.L.; Baccarani, U.; Favero, A.; Zompicchiati, A.; Bresadola, F.; Uzzau, A. Liver resective surgery: A multivariate analysis of postoperative outcome and complication. Langenbeck’s Arch. Surg. 2006, 392, 45–54.
89 - Arikawa T, Kurokawa T, Ohwa Y, et al. Risk factors for surgical site infection after hepatectomy for hepatocellular carcinoma. Hepatogastroenterology. 58(105):143-146. http://www.ncbi.nlm.nih.gov/pubmed/21510302. Accessed October 8, 2018
90- Winter, K.S.; Greif, V.;Crispin, A.; Burgard, C.; Forbrig, R.; Liebig, T.; Trumm, C.G.; Stahl, R. CT-Guided Drainage of Fluid Collections Following Liver Resection: Technical and Clinical Outcome of 143 Patients during 14-Year Period. Diagnostics 2021, 11, 826.
91- Mulé S, Colosio A, Cazejust J, Kianmanesh R, Soyer P, Hoeffel C. Imaging of the postoperative liver: review of normal appearances and common complications. Abdom Imaging. 2015;40(7):2761-2776. doi:10.1007/s00261-015-0459-z
92- Brustia, R.; Fleres, F.; Tamby, E.; Rhaiem, R.; Piardi, T.; Kianmanesh, R.; Sommacale, D. Postoperative collections after liver surgery: Risk factors and impact on long-term outcomes. J. Visc. Surg. 2020, 157, 199–209.
93-Rathmann, N.; Haeusler, U.; Diezler, P.; Weiss, C.; Kostrzewa, M.; Sadick, M.; Schoenberg, S.O.; Diehl, S.J. Evaluation of Radiation Exposure of Medical Staff During CT-Guided Interventions. J. Am. Coll. Radiol. 2015, 12, 82–89.
94- Vansonnenberg, M.E.;Wittich, M.G.R.; Goodacre, M.B.W.; Casola, M.G.; D’Agostino, M.H.B. Percutaneous Abscess Drainage: Update. World J. Surg. 2001, 25, 362–369.
95- Dorcaratto D, Mazzinari G, Fernandez M, et al. Impact of Postoperative Complications on Survival and Recurrence After Resection of Colorectal Liver Metastases. Ann Surg. February 2019:1. doi:10.1097/SLA.0000000000003254
Published
2023-03-16
How to Cite
Parada, U., Delgado, J., Pereyra, J., Andreoli, G., & Cazabán, L. (2023). Physiopathological changes and complications of liver resections. Anales De La Facultad De Medicina, 10(1), e301. https://doi.org/10.25184/anfamed2023v10n1a6
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Artículos de revisión
Copyright (c) 2023 Ulises Parada; Juan Delgado; Joaquín Pereyra; Gustavo Andreoli; Luis Cazabán
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